Global alarm as drug-resistant fungal infections surge

Around the world, there is an increasing number of infections caused by drug-resistant fungi. According to the latest research published in the renowned scientific journal "Pathogens and Immunity", there are over 150 million serious infections annually, nearly 2 million of which result in death.

Fungal infections, also referred to as skin fungi, can be contracted through contact with microorganisms found in the soil or on the surfaces of various objects, like public showers. Another way to contract an infection can be through another person or pets that carry the fungi. Symptoms of such an infection typically include a rash, itching, burning, and skin irritation.

In light of epidemiological data published in the journal "Microbial Cell", there are over 150 million serious fungal infections worldwide each year, and almost 1.7 million of them result in the patient's death.

Professors of dermatology, Thomas McCormick and Mahmoud Ghannoum, from Case Western Reserve University School of Medicine, in their article published in "Pathogens and Immunity", are raising concerns about the increasing number of global fungal infections that are resistant to drugs. McCormick points out that "this is not just a problem that affects individual patients". The World Health Organization (WHO) has recognized this as a broad threat that, if not addressed, could impact entire healthcare systems.

Particularly alarming is the emergence of multi-drug resistant fungus species such as Candida auris and Trichophyton indotineae. Patients undergoing cancer surgeries and transplants, who are receiving medications that suppress the immune system, are especially susceptible to this type of infection.

In a study, recently published in the journal "Emerging Infectious Diseases", the research team led by Ghannoum, in collaboration with the Centers for Disease Control and Prevention (CDC), detailed a case of the fungus Trichophyton indotineae, which not only has become resistant to drugs but also is transmitted sexually. This species, identified in India, has been found in China, Vietnam, European countries, Canada, and Australia, as well as in the United Arab Emirates and Iran.

The authors of the study emphasize that appropriate actions are needed to protect people from multi-drug resistant fungi. This starts with education and increasing awareness about the topic. Ghannoum notes that "healthcare providers must prioritize the use of diagnostic tests in the case of an unknown fungal infection". Early detection can significantly improve patient outcomes.

Source: PAP

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